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M9480651.TXT
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1994-08-20
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Document 0651
DOCN M9480651
TI [Prevention of MAI infections in AIDS with Ansatipine: experience at a
hospital. From an interview with Dr. Jean-Luc Meynard]
DT 9410
AU Meynard JL; Service des Maladies Infectieuses et Tropicales du Pr
Frottier,; Hopital Saint-Antoine, Paris.
SO Allerg Immunol (Paris). 1994 Apr;26(4):155-7. Unique Identifier :
AIDSLINE MED/94304500
AB Nowadays, infections by the Mycobacterium avium complex (MAC) have
become amongst the most frequent of the opportunistic bacterial
infections in AIDS, following the introduction of prophylaxis to
pneumocystosis and toxoplasmosis. MAC infections are recognised as a
serious pathology that quickly causes hidden conditions then death of
the patient after a short time and so there is need for an effective
prophylaxis. In this context, rifabutine (Ansatipine) fills the
therapeutic gap and is needed by both practitioners and patients who are
affected by these serious infections. For several months, the AIDS
committee of the Hopital Saint-Antoine in Paris has advised the
systematic introduction of prophylactic treatment by Ansatipine, after
proper prescriptive indications, for HIV patients both in hospital and
in outside consultations. Retrospective analysis after 2 1/2 months of a
population sample of 32 patients, mostly non hospitalised but followed
by the Service of Infectious Diseases of the hospital and receiving
Ansatipine, showed no documented infection by MAC in the patients whose
quality of life was very satisfactory. Furthermore, the prophylactic
treatment was well-tolerated without any withdrawals. Today,
distribution of Ansatipine to town pharmacies can only improve the lives
of patients and encourage practitioners to profit from a treatment of
indisputable benefit.
DE AIDS-Related Opportunistic Infections/EPIDEMIOLOGY/MICROBIOLOGY/
*PREVENTION & CONTROL Drug Evaluation English Abstract Female
Hospitals Human Male Mycobacterium avium-intracellulare
Infection/EPIDEMIOLOGY/ *PREVENTION & CONTROL Retrospective Studies
Rifabutin/*THERAPEUTIC USE INTERVIEW JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).